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KMID : 0390620130210030140
Journal of Cardiovascular Ultrasound
2013 Volume.21 No. 3 p.140 ~ p.144
Device Closure of a Large Atrial Septal Defect in a Patient with Severe Pulmonary Arterial Hypertension after 1 Year Use of an Oral Endothelin Receptor Antagonist
Jung In-Hyun

Lee Sang-Yun
Lee Sook-Jin
Lee Joo-Young
Park Nam-Jin
Ahn Dea-Sung
Jung Jae-Hoon
Shin Dong-Hee
Lim Dal-Soo
Abstract
The presence of severe pulmonary arterial hypertension (PAH) in patients with atrial septal defect (ASD) is still thought to preclude shunt closure, although there are several reports of good clinical outcomes after vasodilator therapy. We report the case of a young woman with ASD and severe PAH who was able to successfully undergo percutaneous shunt closure following 1 year use of the oral endothelin receptor antagonist, bosentan.
KEYWORD
Atrial septal defect , Pulmonary hypertension , Septal occlude device
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